Kupiansk or Kupyansk is a city in Kharkiv Oblast, Ukraine. It serves as the administrative center of Kupiansk Raion. It is also an important railroad junction for the oblast. Kupiansk hosts the administration of Kupiansk urban hromada, one of the hromadas of Ukraine. It had a population of 26,627. In February 2024, more than 3,500 people remain in Kupyansk.