Interstate 80 was closed in Green River after the crash and will likely remain so until at least Wednesday, officials said. The roadway runs from San Francisco nearly to New York City.

At least two people were killed in a "multi-vehicle crash" in an interstate tunnel, Wyoming authorities confirmed Friday.

The crash occurred at 11:37 a.m. under a snow-dusted hill in Green River, Wyo., according to the State Transportation Department. By 5 p.m., the tunnel, which leads traffic west on Interstate 80, had been evacuated and the scene had “been contained,” the department said in a statement.

A fiery multi-vehicle pileup caused by a crash inside an interstate tunnel has claimed the life of a third person. Wyoming Department of Transportation confirmed the death, though no further details have been given.

The eastbound Green River tunnel on Interstate 80 has reopened almost a week after a fiery crash that left three people dead.

A fiery pileup at a tunnel on Interstate 80 in southwestern Wyoming killed at least two people, seriously injured at least five others and shut down the highway.

About half of the vehicles involved in the Feb. 14 Green River tunnel fire have now been cleared by the Wyoming Highway Patrol

A third victim was found Sunday in the wreckage from a fiery crash inside a Wyoming highway tunnel that involved 26 cars and trucks, officials said.