Alpha synuclein is a presynaptic protein that, when misfolded, contributes to neuronal degeneration and the progression of ...

Researchers have developed an infrared-based sensor that detects misfolded alpha-synuclein protein in spinal fluid with ...

Professor, Aarhus University, Dept. of Biomedicine (West), Director, DANDRITE, Danish Research Institute of Translational Neuroscience, (Nordic EMBL partnership for Molecular Medicine). Co-founder and ...

New data show that blarcamesine completely rescued impaired motor functionBiomarker of nerve fiber density of dopaminergic nerve cells indicating ...

Amsterdam, July 22, 2024 – To date Parkinson's disease (PD) is diagnosed clinically and rather late in the course of the disease. There is an urgent need to find an objective, quantifiable biomarker ...

Skin biopsies detected phosphorylated alpha-synuclein in a high proportion of people with Parkinson's disease and other synucleinopathies. Finding a reliable diagnostic biomarker for synucleinopathies ...

“Taken together, our findings highlight both brain region-specific vulnerabilities and global molecular perturbations associated with alpha-synuclein biology and provide insights into early ...

“These are the first data to link ASC speck assembly, NLRP1 inflammasome activation, and alpha-synuclein aggregation in neurons of Parkinson’s disease patients,” said Stephen C. Glover, ZyVersa’s ...

A new study has revealed how the mutated proteins that are a hallmark of Parkinson’s disease spread and aggregate in the brain. The finding opens the door to developing a way of halting the disease’s ...