Single-cell RNA sequencing has transformed biology by showing which genes are active in individual cells. However, this approach requires cells to be removed from their natural environment, erasing ...
Scientists have uncovered a surprisingly simple “tissue code”: five rules that choreograph when, where, and how cells divide, move, and die, allowing organs like the colon to remain flawlessly ...
Gene expression reveals that different types of human cell can work as a unit. These cellular modules, found in several tissues, change during disease. However, suitable computational methods are ...
New simulator and computational tools generate realistic ‘virtual tissues’ and map cell-to-cell ‘conversations’ from spatial transcriptomics data, potentially accelerating AI-driven discoveries in ...
Researchers at Helmholtz Munich and the Technical University of Munich (TUM) have developed Nicheformer, the first large-scale foundation model that integrates single-cell analysis with spatial ...
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Intercellular fluid flow, not just cell structure, governs how tissues respond to physical forces
Subscribe to our newsletter for the latest sci-tech news updates. Now, MIT engineers have found that this "intercellular" fluid plays a major role in how tissues respond when squeezed, pressed, or ...
Epithelial tissues are in constant interaction with their environment. Maintaining their functionality requires dynamic balance (homeostasis) and that their cell numbers are tightly regulated. This is ...
The hiFlow in vitro platform. a Schematic of the hiFlow chip (backside view), with the components of the microfluidic network highlighted in the design. Each chip hosts two microfluidic networks and ...
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