A virus relies on the host's translation machinery to replicate itself and become infectious. Translation efficiency ...
This is a summary of: Liu. H. et al. Viral RNA blocks circularization to evade host codon usage control. Nature https://doi.org/10.1038/s41586-025-09809-y (2025).
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Deep learning–based codon optimization framework boosts protein expression in E coli
By combining Transformer-based sequence modeling with a novel conditional probability strategy, the approach overcomes ...
To overcome the inherent challenge of translation termination interference caused by stop codon reprogramming in mammalian cells, researchers from Peking University led by Chen Peng from College of ...
The other known alternate sense codon use among yeast was first identified in Candida albicans two decades ago. This too involves a CUG codon, but results in serine in the translated protein. “For ...
Living organisms synthesize a staggering variety of proteins by combining 20 amino acids into chains of any length and order. In the past, to expand protein diversity beyond the scope of these 20 ...
A virus relies on the host's translation machinery to replicate itself and become infectious. Translation efficiency ...
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