The Indianapolis Colts have had injuries derail what looked like a promising season. Everyone knows the team lost QB Daniel ...

SportsLine's model simulated Indianapolis vs. San Francisco on 'MNF' 10,000 times and reveals its NFL picks today ...

The NFL season is ending today, and bettors could win big in this AFC South match-up between the Indianapolis Colts and the Houston Texans at NRG Stadium.

Head Coach Kyle Shanahan and the Niners now control their fate in their pursuit of the NFC West crown and the top overall seed in the NFC. The scary part for the rest of the NFC is San Francisco is ...

The Indianapolis Colts are allowing three defenders to have a chance to join the squad after holding workouts today.

INDIANAPOLIS — The Indianapolis Colts are in Seattle to take on the Seahawks as they look to keep their season alive after losing four of their last five games. Injuries are the theme of the afternoon ...

The Indianapolis Colts are 8-5 and were leading the AFC just a few weeks ago. This week, they're projected to lose by two touchdowns. Give or take, that's how the betting lines are looking at the ...

Get the best 49ers vs. Colts predictions and odds ahead of Week 16 Monday Night Football on December 22, 2025. Take the Over.

That's why they play the games. The Indianapolis Colts entered the 2025 season with a one-way ticket to a top-five pick in the 2026 NFL Draft. No one game them a chance with Daniel Jones as the ...

Philip Rivers had just completed a key third down to Alec Pierce, but this time the Colts were close to kicker Blake Grupe's ...

The 8-5 Indianapolis Colts continued their free fall with a third consecutive loss, and have lost Daniel Jones ahead of traveling across the country to take on the 10-3 Seattle Seahawks on Sunday, ...