Now, the model has analyzed Colts vs. 49ers on 'Monday Night Football' and locked in three confident best bets for an NFL SGP. If you successfully parlay its picks, you'd be looking at a payout of well over 6-1. You can only see the Machine Learning Model player prop predictions for San Francisco vs. Indianapolis here.

The San Francisco 49ers have beaten the Indianapolis Colts 48-27 on “Monday Night Football” behind Brock Purdy ’s career-high five touchdown passes. Christian McCaffrey racked up 146 total scrimmage yards and caught two touchdowns, while George Kittle totaled seven receptions for 115 yards and a TD before leaving the game with an ankle injury.

Todd Blackledge (Analyst), and Kathryn Tappen (Sideline Reporter) to Call Ravens-Packers on Saturday at 8 p.m. ET on Peacock; Coverage begins with a Special Edition of Football Night in America at 7:30 p.

The Indianapolis Colts will look to snap a four-game losing streak when they battle the San Francisco 49ers on Monday Night Football. San Francisco is coming off a 37-24 win over the Tennessee Titans on Sunday,

The San Francisco 49ers did not play their best game against the Carolina Panthers on Monday Night Football last night. Despite this, they were able to pull off the 20-9 victory and improved to 8-4 on the season. Most importantly, they maintained their ...

The Falcons could not get out of their own way for most of Thursday night, but they somehow pulled out a 29-28 upset of the Bucs on the final play. Zane Gonzalez’s 43-yard field goal was a dagger to the Bucs’ playoff hopes.

It's been a wild 2025 NFL season, with some teams thriving and others struggling in what's been a mostly tight set of standings. But if you're here, you might be wondering: Is there any NFL football to watch on this Thursday night like there will be the ...

Josh Lewnberg: After sitting out last night in Milwaukee for injury management on his lower back, Jakob Poeltl is listed as questionable for tomorrow’s game vs Boston due to… you guessed it… injury management on his lower back. RJ Barrett, who should be ramping up soon, is still out.