A new review highlights how human evolution has shaped the presence of pathogenic variations in DNA damage repair (DDR) genes, offering a new perspective on why modern populations face increased ...

Genetic variation within Drosophila populations underpins our understanding of how organisms adapt to changing environments. As a premier model, Drosophila offers finely resolved genomic tools and ...

Genome assemblies from 65 individuals, representing a variety of the world’s populations, are advancing the scientific exploration of complex genetic structural variation. Structural variations are ...

Genes make us who we are—but are they shaped by chance, natural selection, or something else?

Depression is a highly common mental health condition that affects millions of people worldwide. Medical professionals have ...

Scientists at USC have definitively demonstrated that large sets of variations in the genetic code that do not individually appear to have much effect can collectively produce significant changes in ...

Structural variants (SVs) are alterations in the DNA sequence that involve large-scale changes, typically longer than 50 base pairs. Advances in long-read sequencing have significantly increased ...

Prostate cancer has distinct genetic properties in different groups of men that can be targeted to improve patient outcomes, UVA Cancer Center researchers have discovered. Based on new findings in ...

What Is the MTHFR Gene Mutation? The MTHFR gene mutation is a variation in the MTHFR gene. This gene normally tells your body how to make the MTHFR protein. You need this protein to process folate, ...

DNA analysis revealed that Cape leopard cubs have developed unique adaptations to survive in mountainous, food-scarce areas of Africa.