Blocking a tumor antioxidant restored T cell activity and made some resistant cancers more responsive to immunotherapy in mice.
In a paradigm-breaking study, researchers have discovered a novel way the immune system, specifically T cells, attack their target cells, reshaping long-held assumptions in immunology and ...
Researchers from the University of California San Francisco proposed to combine expandable, genetically modifiable human induced pluripotent stem cells (hiPSCs) with tumor-membrane “dressing” to ...
In a paradigm breaking study, Dr. Pavan Reddy, director of the Dan L Duncan Comprehensive Cancer Center at Baylor College of Medicine (BCM) and his team, in collaboration with Drs. Arul Chinnaiyan, S ...
Fusion-loop mutations shifted Zika vaccine protection onto CD8 T cells while weakening antibodies against mature virus.
CAR T-cell therapy has reshaped the treatment landscape of hematologic malignancies, delivering deep and often durable responses across multiple disease settings. 1 In solid tumors, however, progress ...
In a paradigm breaking study, Dr. Pavan Reddy, director of the Dan L Duncan Comprehensive Cancer Center at Baylor College of Medicine (BCM) and his team, in collaboration with Drs. Arul Chinnaiyan, S ...