President Donald Trump on Sunday issued a stark warning to Iran against retaliating on U.S. targets in the Middle East while also predicting Israel and Iran would “soon” make a deal to end their escalating conflict.

"The full strength and might of the U.S. Armed Forces will come down on you at levels never seen before," Trump warned.

The Washington-based group Human Rights Activists reported a far higher death toll in Iran from Israeli strikes, saying the attacks have killed at least 406 people and wounded another 654. In recent crises, Iran routinely has undercounted casualties, including in the 2022 mass demonstrations over mandatory hijab laws after the death of Mahsa Amini.

DUBAI, United Arab Emirates (AP) — Israel launched an expanded assault on Iran on Sunday, with direct strikes targeting its energy industry and Defense Ministry headquarters, while Tehran unleashed a fresh barrage of missiles blamed for the deaths of four people and injuries of many others.

Israel and Iran have opened a new chapter in their long history of conflict when Israel launched a major attack with strikes early Friday on Tehran.

Iran conflict could open opportunities for Russia to possibly become a power broker to help end the confrontation.

Anger is mixed with worry as Iranians in the capital of Tehran woke up Saturday to images of their country’s retaliatory attacks on Israel.

Israel launched a wave of unprecedented strikes on Iran shortly before sunrise Friday morning, hitting key sites in the nation’s nuclear program.