Phillip Rivers leads the Indianapolis Colts against Brock Purdy and the San Francisco 49ers tonight in this NFL Week 16 showdown.

Caesars Sportsbook pioneered live streaming NFL games in December 2022 by launching its "Watch & Bet" feature for both regular-season and playoff matchups. Since then, Caesars has improved the experience with "BetVision," a built-in viewing tool that lets you watch games, check live odds, place bets, and manage your bet slip all in one place.

Fans can listen to Monday Night Football live with SiriusXM on channel 88, NFL Radio, for the national broadcast. Team-specific channels are available, with 225 being the Colts and 226 being the 49ers.

The Tennessee Titans, led by quarterback Cam Ward, face the San Francisco 49ers, led by quarterback Brock Purdy, on Sunday, Dec. 14, 2025 at Levi’s Stadium in Santa Clara, Calif.

The Colts host the 49ers on "Monday Night Football" to wrap up Week 16. Here's where to watch, stream, the start time and predictions.