Clinical trial datasets are becoming increasingly complex, yet the format of their dissemination remains largely static.1 ...

Type 1 diabetes confers a cardiovascular burden that is often obscured by the young age of affected individuals and by the longstanding focus on microvascular rather than macrovascular complications.

Urinary stone disease is common, associated with substantial morbidity, has a high recurrence rate, and affects quality of life.1,2 Consumption of large volumes of fluids is a foundational strategy ...

We read with interest the results of the HARMONi-6 trial by Zhiwei Chen and colleagues,1 which showed that ivonescimab plus chemotherapy improved progression-free survival versus tislelizumab plus ...

Respiratory medicine is deeply connected to social and structural determinants of health in terms of the diseases that we try to prevent and we treat. I think that connection to people's lives and ...

Among today's most pressing development challenges is the matching of financing to health needs. One of the critically underfunded global priorities is adolescent health, with adolescents (aged 10–24 ...

The 2021 Lancet Commission on diagnostics reported that nearly half of the world's population has limited access to basic diagnostic services.1 Less than 5% of diagnostics and less than 1% of vaccines ...

Between Nov 24 and Nov 27, 2025, the International Chair in Bioethics held its 17th World Conference on Bioethics, Medical Ethics, and Health Law in Ljubljana, Slovenia.1 Despite being hosted in a ...

Although malaria elimination has been reported in 14 countries, human health risk reduction against vector-borne diseases remains dire. With neither effective treatment nor widely available ...

GLP-1 receptor agonist indications continue to expand beyond glycaemic and weight control, with benefits now shown in chronic kidney disease in type 2 diabetes, obesity-related heart failure, knee ...

In 2021, a global tuberculosis vaccine research and development roadmap proposed a series of actions to accelerate the development of new, effective, and affordable vaccines that are urgently needed ...

Men and partners are important contributors to the health of future generations, yet their own preconception health and wellbeing remain secondary considerations in research, practice, and policy.