An American Airlines regional jet went down in the Potomac River near Ronald Reagan Washington National Airport.

US airlines had gone 16 years without a fatal crash until Wednesday night. But as impressive as that safety record had been, there have been warning signs in recent years of a significant risk of a collision like the one that just killed 67 people.

American Airlines CEO Robert Isom said that Flight 5342 was on a normal approach to Reagan National Airport and that “we don’t know why the military aircraft came into the path of the PSA aircraft,” one of the many questions the Fort Worth-based carrier is asking in the wake of the tragedy that took 67 lives.

The American Airlines’ subsidiary has ties that go back decades in Ohio, and just said it was moving its headquarters to Charlotte.

A family with Georgia ties is grieving after learning their loved one was one of the pilots killed in the crash between a small American Airlines plane and a military helicopter crash near Reagan National Airport.

D.C. police confirmed a crash had taken place over the Potomac and that search and rescue operations were taking place in the river. Donald Trump later weighed in.

“A PSA Airlines Bombardier CRJ700 regional jet collided in midair with a Sikorsky H-60 helicopter while on approach to Runway 33 at Reagan Washington National Airport around 9 p.m. local time,” the Federal Aviation Administration (FAA) said in a statement.

Both the captain, Jonathan J. Campos, 34, and co-pilot, Sam Lilley, 28, had been flying for years, according to family and friends.

American Airlines Group Inc. (NASDAQ: AAL) owns PSA, which already has a large presence in Charlotte, operating regional flights on American’s behalf. American is based in Fort Worth, Texas, but runs its second-largest hub at Charlotte Douglas, known as CLT.

An American Airlines flight operated by PSA Airlines was involved in a midair collision with a military helicopter on Wednesday night near Washington, D.C.

PSA Airlines, a regional airline and subsidiary of American Airlines Group, announced today that it will relocate its corporate headquarters from Dayton, Ohio, to Charlotte, North Carolina, by026.