During the COVID-19 pandemic, when fentanyl overdoses surged, doctors were desperate to find ways of helping their patients. They knew that buprenorphine could help people stop using opioids, but it was much harder to start the treatment for those who used ...

Background: Fentanyl, a short-acting synthetic opioid, has a pharmacokinetic profile suited to fast relief of brief episodic pain. Objective: To characterize the pharmacokinetic-pharmacodynamic ...