Hundreds of civilians, mostly in Iran, have been killed by dueling airstrikes despite international pleas for de-escalation.

Iran fired a new wave of missile attacks on Israel early today killing at least eight people and injuring 70, authorities in Israel have said.Explosions rocked major Israeli cities, including Tel Aviv and the port city of Haifa.

Israel’s massive airstrike attack left Iran’s military leadership in crisis as it killed several senior Iranian commanders — including the head of its Revolutionary Guard.

Follow live updates as Iran retaliates after Israel strikes nuclear facilities. Stay informed with real-time news and developments.

Unconfirmed reports by Iran's opposition claim that the Supreme Leader, Ayatollah Ali Khamenei, was killed during Israel's strikes on Tehran.

Israel and Iran kept up their attacks, killing and wounding civilians and raising concern among world leaders meeting in Canada this week that the biggest battle between the two old enemies could lead to a broader regional conflict.

President Trump joked that Iranian officials killed in Israel's airstrike clearly did not die of an illness, warning that Iran should have heeded his warning.

Sirens sounded in Israel as the Israel's military said Iran launched ballistic missiles and more than 100 drones in what appeared to be the start of Iranian retaliation for Israeli strikes on its nuclear facilities.