(p)ppGpp, through its interaction with RNA polymerase, aids in managing replication conflicts and facilitates the loading of ...

Bacteria frequently encounter adverse environmental conditions, such as nutrient scarcity and antibiotic exposure, which can induce DNA damage ...

PARP1 is critical for repairing DNA single-strand breaks. First-generation PARP1/2 inhibitors have proven effective in the treatment of tumors with mutations in the essential homologous recombination ...

What is DNA, and how does it work? You don't need a degree in genetics to understand. Here, we'll give an overview of DNA and ...

The damage in question is the DNA double-strand break ... has the unique ability to visualize the behavior of DNA repair proteins on a single DNA molecule in real time. They show in this study ...

The damage in question is the DNA double-strand break ... has the unique ability to visualize the behavior of DNA repair proteins on a single DNA molecule in real time. They show in this study ...

Research led by The University of Texas Health Science Center at San Antonio shows that the breast cancer gene 1 (BRCA1) not only pushes accurate DNA repair to guard against cancer but promotes ...

Science DNA breaks are toxic lesions for the cell. In order to repair these breaks, it is necessary, starting from the break ends, to find a homologous sequence within the vastness of the genome. In ...

We have seen a new effective single ... of DNA damage that results from tumor specific PTGR1 HITEN expression for which now we have bioassay, which causes bioactivation of LP-184 in tumor cells is ...