The bruised and battered San Francisco 49ers will need these five players to step up against the short-handed Los Angeles ...

San Francisco 49ers quarterback Brock Purdy spoke about orchestrating the team's offense without playmakers Christian ...

According to Tallysight, a whopping 96% of experts are picking the 49ers to beat the Rams. It’s slightly better when ...

The San Francisco 49ers will face the Los Angeles Rams on Sunday without wide receiver Deebo Samuel and running back ...

Herbert injured his right leg in the third quarter of Week 2’s 26-3 win against the Carolina Panthers trying to escape the ...

Week 3 matchup vs. Rams with key injuries to McCaffrey, Samuel, and Kittle, testing their depth in this crucial NFC West ...

Injuries have caused many problems for the San Francisco 49ers this year, and now Brock Purdy has lost another offensive ...

The San Francisco 49ers could be without another key offensive player this week after All-Pro tight end George Kittle missed ...

The Niners will perhaps be without arguably their three most important offensive weapons, sidelined stars Christian McCaffrey ...

One game down, three more to go until Christian McCaffrey is eligible to come off Injured Reserve. The San Francisco 49ers placed McCaffrey on I.R. on Sept. 14 ...