Why fork over thousands of dollars a month for prescription weight loss jabs when store-bought supplements claim to have the same effect?

Natural supplements have “very mild effects” on weight loss based on what Dr. Ali has seen. There is some data to suggest that saffron, green tea, or turmeric can have a slight impact on GLP-1 production, he says, but again, it's not a ton.

While both berberine and Ozempic may lead to weight loss, they are very different things. It’s “inaccurate and misleading” to call berberine “nature’s Ozempic,” Dr. Ali says, noting that they work differently in the body and have very different weight loss results.