Shares of Lexeo Therapeutics (NASDAQ:LXEO) dropped about 17% on Monday after the company published interim Phase I/II results for its PKP2 gene therapy candidate, LX2020, being developed for ...

Proteinuria (protein in urine) is common with complement 3 glomeropathy and is a strong predictor of disease progression and end-stage kidney failure.

LX2020 generally well tolerated across ten participants with no clinically significant complement activation LX2020 transduction, transcription, ...

From football fields to military training grounds, head injuries are leaving lasting marks on the brain in ways we're only ...

Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. The complement system plays crucial roles in ...

Introduction Cell-bound complement activation products (CB-CAPs) in a multi-analyte assay with algorithm (MAP) is a valuable biomarker for the diagnosis of SLE. Erythrocyte-bound complement activation ...

Copyright: Published by Elsevier Ltd. The complement system is recognised as a protector against blood-borne pathogens and a controller of immune system and tissue ...

Can scientists who study Alzheimer’s disease find a solution to ARIA? These amyloid-related imaging abnormalities, which reflect brain edema, microbleeds, and occasionally large brain bleeds, have ...

Background Complement activation plays a critical role in the development of kidney injury during lupus nephritis (LN). Clinical trials targeting the complement pathway are now underway in LN. It is ...