Mary Brunkow, Fred Ramsdell, and Shimon Sakaguchi were awarded the 2025 Nobel Prize in Physiology or Medicine on Monday for their collective work in the discovery of specialized immune cells that roam ...
Among patients with pancreatic cancer, the vaccine ELI-002 7P elicited strong mKRAS-specific T cell responses in approximately 99% of patients. In an announcement, the off-the-shelf vaccine ELI-002 7P ...
State Key Laboratory of Biopharmaceutical Preparation and Delivery, Institute of Process Engineering, Chinese Academy of Sciences, No. 1 Bei-er-jie, Haidian District, Beijing 100190, China Division of ...
Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. Vaccination offers the most effective ...
Despite the massive use of vaccines against Avian encephalomyelitis virus (AEV), outbreaks of the disease that may be associated with low flock immunity are still reported. This study aimed to ...
NOTCH1 expression levels are crucial in determining treatment response in SCLC, with higher levels linked to better outcomes. Activation of NOTCH1 reactivates the STING pathway, increasing MHC Class I ...
RA patients on upadacitinib and methotrexate showed robust antibody and T-cell responses to the recombinant zoster vaccine over 60 weeks. The vaccine maintained a satisfactory humoral response in 71.4 ...
The false call was directed at a student dormitory, officials said. For the second time in less than a week, Villanova University was the scene of an active shooter hoax report on Sunday, prompting ...
Malaria is a life-threatening illness spread through mosquitos. According to the World Health Organization (WHO), in 2023 there were over 200 million cases of Malaria with 76% of all deaths being ...
THE HUMAN immune system is full of surprises. Though it has long been known that the body’s internal defences spring into action when an infection-causing intruder—such as a bacterium or virus—is ...
Among patients undergoing maintenance dialysis, chronic heart failure and hypoalbuminaemia were significantly associated with a poor humoral response at 3 months after completing three doses of the ...
Traditionally, insects have been thought to be entirely dependent on their innate immune system, which has little capacity for the acquisition of experience from previous infections. However, much ...
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