Bacteria frequently encounter adverse environmental conditions, such as nutrient scarcity and antibiotic exposure, which can induce DNA damage ...

(p)ppGpp, through its interaction with RNA polymerase, aids in managing replication conflicts and facilitates the loading of ...

DNA repair after Cas9-mediated double-strand ... base editors and prime editors leveraging Cas9 nickases producing single-strand breaks. Cytosine base editing is crucial for modeling human ...

POLK expression in neurons and report an important observation that POLK exhibits an age-dependent change in subcellular localization, from the nucleus in young tissue to the cytoplasm in old tissue.

Science DNA breaks are toxic lesions for the cell. In order to repair these breaks, it is necessary, starting from the break ends, to find a homologous sequence within the vastness of the genome. In ...

What is DNA, and how does it work? You don't need a degree in genetics to understand. Here, we'll give an overview of DNA and ...

PARP1 is critical for repairing DNA single-strand breaks. First-generation PARP1/2 inhibitors have proven effective in the treatment of tumors with mutations in the essential homologous recombination ...

Promoted cards do not include input from individual authors. For single parents, these responsibilities compound. If you're a single parent, you're certainly not alone: There were an estimated 9.8 ...

In theory, a single gram of DNA could store 215,000 terabytes of data, but since the first demonstration of its data storage potential, scientists have struggled to show how it could become part of a ...

Sara Runnels was known for her humorous stories and social media shares about the single life, but her dating status quickly changed after meeting Adam Zack. By Jenny Block The day after her ...

Sofía Vergara claims she’s “kind of single” despite being romantically involved with beau Dr. Justin Saliman as she gave a vague update on her relationship status. The “Modern Family ...

They were able to extract DNA from a single premolar tooth taken from the mandible. The tooth's cementum and enamel were removed, the tooth was ground into powder, and the sample was zapped with ...