San Francisco 49ers running back Christian McCaffrey will be eligible off the injured reserve after Week 6, but could still miss a pivotal Week 7 Super Bowl rematch with the Kansas City Chiefs.

The San Francisco 49ers will likely be without All-Pro tight end George Kittle for Sunday's game against the Los Angeles Rams ...

Two of the best wide receivers in the NFL are expected to be on the field for their respective Week 3 games. Justin Jefferson ...

The NFL's reigning Defensive Player of the Year returned to ... The Niners will also be without All-Pro running back ...

In an interview on "The Insiders", Pittsburgh Steelers linebacker Alex Highsmith talks about his team's defensive identity ...

New England Patriots head coach Jerod Mayo explains that Patriots quarterback Jacoby Brissett "is our quarterback until I say ...

San Francisco 49ers' George Kittle is listed as doubtful for Sunday's game against the Rams. He joins Christian McCaffrey and ...

J.B. Long examines how both the Los Angeles Rams and San Francisco 49ers are dealing with significant injuries on the ...

The San Francisco 49ers (1-1) are visiting the Los Angeles Rams (0-2) on Sunday afternoon in a rivalry game between NFC West ...

Darnold has quietly been one of the best quarterbacks in the NFL this season. Through two weeks, Darnold has completed 72 ...

The NFL’s Week 3 injury report is live. Will Justin Herbert play? Find out which players are on the injury report.

San Francisco 49ers quarterback Brock Purdy will be tested in the coming weeks with the absence of key offensive weapons.