BMJ2d
Etanercept in patients with inflammatory hand osteoarthritis (EHOA): a multicentre, randomised, double-blind, placebo-controlled trial
Correspondence to Professor Margreet Kloppenburg, Department of Rheumatology, Leiden University Medical Center, Leiden 2300 RC, The Netherlands; g.kloppenburg{at}lumc.nl Objective Hand osteoarthritis ...
BMJ27d
Dynamics of the gut microbiome in individuals at risk of rheumatoid arthritis: a cross-sectional and longitudinal observational study
Objectives This work aimed to resolve the conflicting reports on Prevotellaceae abundance in the development of rheumatoid arthritis (RA) and to observe structural, functional and temporal changes in ...
BMJ2d
POS1428 IDENTIFICATION OF A WARM AUTOIMMUNE HEMOLYTIC ANEMIA (wAIHA) POPULATION USING PREDICTIVE ANALYTICS OF A KNOWN CLINICALLY PROFILED COHORT
1 Taussig Cancer Institute, Cleveland Clinic, Hematology and Medical Oncology, Cleveland, OH, United States of America 2 Clinical Communications and Patient Advocacy, Editas Medicine, Medical Affairs, ...
BMJ8d
Vascularised human skin equivalents as a novel in vitro model of skin fibrosis and platform for testing of antifibrotic drugs
Correspondence to Dr Jörg H W Distler, Department of Internal Medicine 3 – Rheumatology and Immunology, Friedrich-Alexander-University Erlangen-Nürnberg (FAU) and University Hospital Erlangen, ...
BMJ13d
Effect of disease duration and prior disease-modifying antirheumatic drug use on treatment outcomes in patients with rheumatoid arthritis
Objectives To determine if disease duration and number of prior disease-modifying antirheumatic drugs (DMARDs) affect response to therapy in patients with established rheumatoid arthritis (RA).
BMJ10d
Synovial macrophage M1 polarisation exacerbates experimental osteoarthritis partially through R-spondin-2
Correspondence to Professor Daozhang Cai and Dr Xiaochun Bai, Department of Orthopedics, Academy of Orthopedics - Guangdong Province, Orthopedic Hospital of Guangdong Province, The Third Affiliated ...
BMJ3d
AB1170 TRANSCUTANEOUS VAGUS NERVE STIMULATION AS A PAIN MODULATOR IN KNEE OSTEOARTHRITIS
Background We no longer consider Osteoarthritis (OA) as a degenerative disease, but rather as a multifactorial disorder in which low grade, chronic inflammation has a central role. In addition, ...
BMJ3d
POS1019 DIPYRIDAMOLE, A COMPOUND THAT INCREASES EXTRACELLULAR ADENOSINE LEVELS, AS A THERAPEUTIC AGENT FOR RHEUMATOID SARCOPENIA
Background In addition to joint damage, rheumatoid arthritis (RA) confers a higher risk of several comorbidities, including changes in body composition with reduced muscle mass and strenght ...
BMJ5d
Single-cell RNA-seq analysis identifies meniscus progenitors and reveals the progression of meniscus degeneration
Correspondence to Dr Zhiqi Zhang, Department of Joint Surgery, Sun Yat-sen University First Affiliated Hospital, Guangzhou 510080, China; zhzhiqi{at}mail.sysu.edu.cn; Dr Weiming Liao; ...
BMJ6d
Immune response profiling of patients with spondyloarthritis reveals signalling networks mediating TNF-blocker function in vivo
Objectives Antitumour necrosis factor (TNF) therapy has revolutionised treatment of several chronic inflammatory diseases, including spondyloarthritis (SpA). However, TNF inhibitors (TNFi) are not ...
BMJ6d
Not only synovitis but also tenosynovitis needs to be considered: why it is time to update textbook images of rheumatoid arthritis
Correspondence to Professor Annette van der Helm-van Mil, Rheumatology, Leiden University Medical Center, Leiden 2300 RC, The Netherlands; A.H.M.van_der_Helm{at}lumc.nl Rheumatoid arthritis (RA) is ...