Effect of propranolol and clonidine after severe traumatic brain …
Jun 9, 2023 · Objective To evaluate the safety, feasibility, and efficacy of combined adrenergic blockade with propranolol and clonidine in patients with severe traumatic brain injury (TBI). …
Background: This systematic review and meta-analysis investigates the efficacy and safety of clonidine as a sedative in critically ill patients requiring invasive mechanical ventilation.
Clonidine for sedation in the critically ill: a systematic review and ...
Feb 25, 2017 · Background This systematic review and meta-analysis investigates the efficacy and safety of clonidine as a sedative in critically ill patients requiring invasive mechanical …
Use of dexmedetomidine in critical-ill patients: is it time to look to ...
Aug 29, 2023 · To the editor Dexmedetomidine is an alpha-2 (ɑ2) adrenergic receptor and imidazoline type 2 receptor agonist that received Food and Drug Administration (FDA) …
Efficacy of haloperidol to decrease the burden of delirium in adult ...
Oct 30, 2023 · Background The role of haloperidol as treatment for ICU delirium and related symptoms remains controversial despite two recent large controlled trials evaluating its …
Sleep and Circadian Rhythm in Critical Illness - Critical Care
Mar 9, 2019 · Numerous follow-up studies have demonstrated an association between depressive symptoms and increased levels of fatigue, stress, and anxiety in healthy participants subject to …
Clinical review: The management of hypertensive crises
Jul 16, 2003 · Clonidine and angiotensin-converting enzyme inhibitors are long acting and poorly titratable, but these agents are particularly useful in the management of hypertensive …
Delirium in the intensive care unit | Critical Care | Full Text
May 14, 2008 · Delirium, an acute and fluctuating disturbance of consciousness and cognition, is a common manifestation of acute brain dysfunction in critically ill patients, occurring in up to …
The effect of dexmedetomidine and clonidine on the inflammatory ...
Dec 11, 2019 · Background The α2 agonists, dexmedetomidine and clonidine, are used as sedative drugs during critical illness. These drugs may have anti-inflammatory effects, which …
Optimizing sedation in patients with acute brain injury
May 5, 2016 · Daily interruption of sedative therapy and limitation of deep sedation have been shown in several randomized trials to reduce the duration of mechanical ventilation and …